Researchers Identify New Epilepsy Gene Network

Researchers Identify New Epilepsy Gene Network

by Kate Wighton, Neuroscience News

Scientists have discovered a gene network in the brain associated with epilepsy

The team, led by scientists at Imperial College London, believe the discovery may lead to more treatments for the condition.

The study, published in the journal Genome Biology, has revealed an ‘epileptic network’ of 320 genes, called M30, that is associated with the condition. The genes in the network are thought to be involved in how brain cells communicate with each other.

The results suggest that when this network malfunctions, it triggers epilepsy. Finding medications that restore this network to normal could provide desperately needed new treatments, explained Professor Michael Johnson, senior author of the research from the Department of Medicine at Imperial.

“Epilepsy is one of the most common serious neurological diseases worldwide. Yet despite almost 30 different drugs licensed for the condition, a third of people with epilepsy continue to suffer from uncontrolled epileptic seizures – despite taking medication.

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