3-D protein structure reveals a new mechanism for future anti-cancer drugs

3-D protein structure reveals a new mechanism for future anti-cancer drugs

by Medical University of South Carolina, Medical Xpress

A research team at the Medical University of South Carolina (MUSC) has discovered a new mechanism for a class of anti-cancer drugs known as E1 inhibitors.

Their findings, published in Nature Communications on December 4, 2018, reveal a novel binding site that will promote drug design of more efficient E1 inhibitors.

The team was led by Shaun Olsen, Ph.D., an assistant professor of Biology and Molecular Biology at MUSC and a member of the Developmental Cancer Therapeutics Program at Hollings Cancer Center.

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